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Domino's pizza slice calories

Domino's pizza slice, 14" cheese, hand-tossed
278kcal
1 cheese slice · 108 g, 14" cheese, hand-tossed
17%protein
11.7 gProtein
36 gCarbs
9.7 gFat
How to burn off 278 kcal
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—Swimming
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Nutrition facts
14" cheese, hand-tossed · per 108 g
Calories278 kcal
Protein11.7 g
Carbohydrate36 g
Fat9.7 g
Saturated fat4.4 g
Cholesterol18 mg
Sodium565 mg
Potassium174 mg
Iron2.5 mg

Source: USDA FoodData Central

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Verified nutrition data

Numbers on this page come from USDA FoodData Central, the U.S. Department of Agriculture’s food composition database, and from manufacturer labels where a branded product is named. Last verified September 2026. How we verify our data →

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Domino's pizza slice FAQs
How many calories are in one slice of Domino's pizza?

A cheese slice from a 14" hand-tossed Domino's pizza (108 g) has about 278 calories; a pepperoni slice (113 g) has about 308.

Is Domino's pizza good for weight loss?

One hand-tossed cheese slice has 278 calories and 9.7 g of fat, while a crunchy thin crust cheese slice is lighter at 209 calories.

Domino's hand-tossed vs thin crust: which has fewer calories?

Thin crust is denser at 298 calories per 100 g versus 257 for hand-tossed, but its slices are smaller, so one slice is 209 calories versus 278.

How much protein is in a slice of Domino's pizza?

A hand-tossed cheese slice has 11.7 g of protein, 35.9 g of carbs and 565 mg of sodium.